Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 12/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091996 | 0.89 | NR1H2 (0.38) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL13601353 | 0.81 | NR1H2 (0.35) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL1092208 | 0.78 | NR1H2 (0.37) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL13601501 | 0.78 | NR1H2 (0.42) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL1092344 | 0.78 | NR1H2 (0.38) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL1092371 | 0.76 | PPARG (0.33) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL1253786 | 0.75 | SLC6A4 (0.48) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL1253782 | 0.74 | NR1H2 (0.38) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL1253784 | 0.74 | NR1H2 (0.38) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL13706681 | 0.74 | PPARG (0.44) | PPARDPPARAPPARGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144961-A1 | SUBSTITUTED CARBINOL COMPOUND HAVING CYCLIC LINKER | 興和株式会社 (JP) | 2009-12-03 | — | — | WO | disclosed |