Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092514 | 0.89 | NR1H2 (0.37) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL13601501 | 0.83 | NR1H2 (0.42) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL13601307 | 0.81 | PPARD (0.38) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1092344 | 0.80 | NR1H2 (0.38) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL1092208 | 0.78 | NR1H2 (0.37) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL13601366 | 0.74 | NR1H2 (0.33) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1091731 | 0.74 | NR1H2 (0.38) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL1091941 | 0.74 | NR1H2 (0.42) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL1091903 | 0.73 | NR1H2 (0.39) | NR1H2NR1H3ARPPARGPPARD | |
| SCHEMBL1092352 | 0.73 | NR1H2 (0.42) | NR1H2NR1H3ARPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144961-A1 | SUBSTITUTED CARBINOL COMPOUND HAVING CYCLIC LINKER | 興和株式会社 (JP) | 2009-12-03 | — | — | WO | disclosed |