Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13608774 | 0.90 | S1PR1 (0.41) | S1PR1MAP4K4MINK1S1PR4S1PR5 | |
| SCHEMBL13601422 | 0.90 | S1PR1 (0.41) | S1PR1MAP4K4MINK1S1PR4S1PR5 | |
| SCHEMBL13601438 | 0.90 | S1PR1 (0.41) | S1PR1MAP4K4MINK1S1PR4S1PR5 | |
| SCHEMBL13601436 | 0.89 | S1PR1 (0.43) | S1PR1MAP4K4MINK1DYRK3MARK3 | |
| SCHEMBL13601406 | 0.89 | S1PR1 (0.43) | S1PR1MAP4K4MINK1DYRK3MARK3 | |
| SCHEMBL13601425 | 0.88 | NPC1 (0.43) | S1PR1MAP4K4MINK1DYRK3MARK3 | |
| SCHEMBL13601413 | 0.86 | S1PR1 (0.39) | S1PR1MAP4K4MINK1DYRK3MARK3 | |
| SCHEMBL13608721 | 0.84 | GRM5 (0.41) | S1PR1 | |
| SCHEMBL13601409 | 0.84 | GRM5 (0.41) | S1PR1 | |
| SCHEMBL13601419 | 0.84 | S1PR1 (0.39) | S1PR1MAP4K4MINK1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | S1PR1 1/4885MAP4K4 3675/4885MINK1 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.