Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | BLVRB | P30043 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601399 | 1.00 | S1PR1 (0.51) | S1PR1MAOABLVRBHDAC6S1PR3 | |
| SCHEMBL13608776 | 1.00 | S1PR1 (0.51) | S1PR1MAOABLVRBHDAC6S1PR3 | |
| SCHEMBL13608781 | 0.94 | S1PR1 (0.46) | S1PR1MAOABLVRBHDAC6S1PR3 | |
| SCHEMBL13601902 | 0.94 | S1PR1 (0.46) | S1PR1MAOABLVRBHDAC6S1PR3 | |
| SCHEMBL13601835 | 0.93 | S1PR1 (0.46) | S1PR1MAOABLVRBHDAC6S1PR3 | |
| SCHEMBL13601412 | 0.92 | S1PR1 (0.43) | S1PR1MAOABLVRBHDAC6S1PR3 | |
| SCHEMBL13601824 | 0.92 | S1PR1 (0.49) | S1PR1S1PR3 | |
| SCHEMBL13601901 | 0.91 | MAOA (0.44) | S1PR1MAOABLVRBHDAC6NPC1 | |
| SCHEMBL13601903 | 0.91 | S1PR1 (0.43) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL13608879 | 0.91 | MAOA (0.44) | S1PR1MAOABLVRBHDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | S1PR1 1/4885MAOA 4558/4885BLVRB 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.