Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.52 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ASPH | Q12797 | 1/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 12/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601817 | 0.92 | EGLN1 (0.59) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL13601815 | 0.84 | EGLN2 (0.50) | EGLN1EGLN2 | |
| SCHEMBL30401668 | 0.81 | EGLN1 (0.55) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL523956 | 0.80 | EGLN1 (0.60) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL523955 | 0.80 | EGLN1 (0.60) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL5316412 | 0.79 | EGLN1 (0.57) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL13601811 | 0.77 | THRA (0.52) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL13601810 | 0.75 | EGLN2 (0.58) | EGLN1EGLN2 | |
| SCHEMBL523845 | 0.75 | EGLN1 (0.86) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL30274439 | 0.75 | EGLN1 (0.86) | EGLN1THRATHRBBBOX1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629357-B2 | Antihypoxic agents; adjust concentration of erythropoietin concentration in blood; strokes; antiepileptic agents; neurodegenerative disease ; liver disorders; antiischemic agents | FIBROGEN, INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629357-B2 | Antihypoxic agents; adjust concentration of erythropoietin concentration in blood; strokes; antiepileptic agents; neurodegenerative disease ; liver disorders; antiischemic agents | FIBROGEN, INC. (US) | 2009-12-08 | — | — | US | disclosed |