Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601824 | 0.91 | S1PR1 (0.49) | S1PR1S1PR3 | |
| SCHEMBL13608781 | 0.90 | S1PR1 (0.46) | S1PR1NPC1RAB9AS1PR3S1PR5 | |
| SCHEMBL13601902 | 0.90 | S1PR1 (0.46) | S1PR1NPC1RAB9AS1PR3S1PR5 | |
| SCHEMBL13601823 | 0.90 | S1PR1 (0.46) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13608776 | 0.88 | S1PR1 (0.51) | S1PR1NPC1RAB9ASMN1; SMN2S1PR3 | |
| SCHEMBL13601432 | 0.88 | S1PR1 (0.51) | S1PR1NPC1RAB9ASMN1; SMN2S1PR3 | |
| SCHEMBL13601399 | 0.88 | S1PR1 (0.51) | S1PR1NPC1RAB9ASMN1; SMN2S1PR3 | |
| SCHEMBL13609293 | 0.88 | S1PR1 (0.53) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13601906 | 0.88 | S1PR1 (0.53) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13601402 | 0.87 | S1PR1 (0.57) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | S1PR1 1/4885KDM4E 3224/4885NPC1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.