Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14712371 | 0.92 | PSMB8 (0.30) | — | |
| SCHEMBL23921488 | 0.89 | HPGD (0.30) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL23950136 | 0.88 | — | — | |
| SCHEMBL19646887 | 0.86 | — | — | |
| SCHEMBL24512525 | 0.86 | PSMB8 (0.32) | — | |
| SCHEMBL14816520 | 0.84 | — | — | |
| SCHEMBL12180768 | 0.84 | — | — | |
| SCHEMBL24174346 | 0.83 | PSMB8 (0.30) | — | |
| SCHEMBL26202805 | 0.83 | PSMB8 (0.33) | — | |
| SCHEMBL19189415 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337823-B2 | Modified macromolecule | STARPHARMA PTY LIMITED (AU) | 2012-12-25 | — | — | US | disclosed |
| US-20090324535-A1 | MODIFIED MACROMOLECULE | STARPHARMA PTY LTD (AU) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324535-A1 | MODIFIED MACROMOLECULE | MRPL11, MAX, MRPL38 | HPGD 2452/4885HTT 2938/4885SMN1; SMN2 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.