⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14816520 | 0.92 | — | — | |
| SCHEMBL14712371 | 0.92 | PSMB8 (0.30) | — | |
| SCHEMBL24863812 | 0.92 | PSMB8 (0.32) | — | |
| SCHEMBL24174346 | 0.89 | PSMB8 (0.30) | — | |
| SCHEMBL19189415 | 0.88 | — | — | |
| SCHEMBL21975910 | 0.88 | — | — | |
| SCHEMBL8214570 | 0.88 | — | — | |
| SCHEMBL12319732 | 0.87 | — | — | |
| SCHEMBL13601925 | 0.86 | HPGD (0.33) | — | |
| SCHEMBL21788087 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407482-B2 | Amino acid substituted molecules | ALLOZYNE, INC. (US) | 2019-09-10 | — | — | US | disclosed |
| US-9827326-B2 | Polymer-sunitinib conjugates | NEKTAR THERAPEUTICS (US) | 2017-11-28 | — | — | US | disclosed |