Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511720 | 1.00 | HTR2C (0.39) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4513969 | 0.90 | GBA1 (0.40) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL13606367 | 0.90 | GBA1 (0.40) | KDM4EALDH1A1HSD17B10HPGDKMT2A | |
| SCHEMBL13606364 | 0.87 | KDM4E (0.40) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4517968 | 0.85 | HTR2C (0.43) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4511725 | 0.84 | HTR2C (0.38) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4875091 | 0.80 | CSNK2B (0.31) | — | |
| SCHEMBL4490087 | 0.78 | HTR2C (0.47) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4506359 | 0.78 | HTR2C (0.47) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL14280912 | 0.78 | CDK2 (0.49) | KDM4EALDH1A1HSD17B10HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |