Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513969 | 1.00 | GBA1 (0.40) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4511720 | 0.90 | HTR2C (0.39) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13606366 | 0.90 | HTR2C (0.39) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13606365 | 0.86 | GBA1 (0.40) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4513974 | 0.83 | GBA1 (0.41) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4875091 | 0.82 | CSNK2B (0.31) | — | |
| SCHEMBL14280912 | 0.80 | CDK2 (0.49) | KMT2AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4874084 | 0.79 | GBA1 (0.39) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13606364 | 0.77 | KDM4E (0.40) | GBA1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13606374 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |