Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.34 |
| ▸ | WEE1 | P30291 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | STK10 | O94804 | 3/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606635 | 0.76 | NPSR1 (0.55) | NPSR1PTPN11CHEK1WEE1GRM5 | |
| SCHEMBL13606638 | 0.74 | NPSR1 (0.54) | NPSR1CHEK1WEE1STK10SLK | |
| SCHEMBL13606628 | 0.73 | CHEK1 (0.34) | CHEK1WEE1PARP1 | |
| SCHEMBL3852142 | 0.72 | PARP1 (0.63) | NPSR1CHEK1WEE1CCNE2CDK4 | |
| SCHEMBL13606633 | 0.70 | NPSR1 (0.52) | NPSR1CHEK1WEE1STK10SLK | |
| SCHEMBL13606492 | 0.70 | GSK3B (0.38) | NPSR1CHEK1WEE1GSK3B | |
| SCHEMBL13606486 | 0.69 | GSK3B (0.37) | NPSR1CHEK1WEE1GSK3B | |
| SCHEMBL19143852 | 0.69 | GSK3B (0.47) | NPSR1CHEK1WEE1CCNE2CDK4 | |
| SCHEMBL13606629 | 0.68 | NPSR1 (0.52) | NPSR1CHEK1WEE1STK10SLK | |
| SCHEMBL7943857 | 0.67 | STK10 (0.41) | CHEK1WEE1CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144205-A1 | RYLENE-BASED SEMICONDUCTOR MATERIALS AND METHODS OF PREPARATION AND USE THEREOF | BASF SE (DE) | 2009-12-03 | — | — | WO | disclosed |