SCHEMBL13607347

SCHEMBL13607347

O=C(Nc1ccn([C@@H]2O[C@@]3(CO)CC4(O)OCO[C@H]2C43)c(=O)n1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.50
RIN1 Q13671 1/20 0.50
POLB P06746 1/20 0.46
P2RY6 Q15077 2/20 0.44
P2RY14 Q15391 2/20 0.44
NT5E P21589 1/20 0.44
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ST6GAL1 P15907 1/20 0.34
P2RY12 Q9H244 1/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
HTR1A P08908 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
HTR1F P30939 1/20 0.33
NPC1 O15118 4/20 0.32
RAB9A P51151 4/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13607349 0.85 ABL1 (0.46) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL12345959 0.81 ABL1 (0.52) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL4773710 0.81 ABL1 (0.54) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL6861475 0.81 ABL1 (0.56) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL25629925 0.78 ABL1 (0.52) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL12345957 0.75 POLB (0.46) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL13722092 0.75 ABL1 (0.52) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL13722163 0.73 ABL1 (0.51) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL12408886 0.73 ABL1 (0.51) ABL1RIN1POLBP2RY6P2RY14
SCHEMBL10072470 0.73 ABL1 (0.51) ABL1RIN1POLBP2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615619-B2 Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof TAKESHI IMANISHI (JP) 2009-11-10 US disclosed