Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668535 | 0.88 | KIF11 (0.57) | KIF11PTGDR2PTPN5CYP11B2AR | |
| SCHEMBL397926 | 0.86 | KIF11 (0.65) | KIF11PTPN5CYP11B2ARNSD2 | |
| SCHEMBL17629903 | 0.82 | KIF11 (0.51) | KIF11PTGDR2PTPN5CYP11B2AR | |
| SCHEMBL1407904 | 0.82 | GLA (0.59) | KIF11PTGDR2PTPN5CYP11B2AR | |
| SCHEMBL17955138 | 0.80 | KIF11 (0.53) | KIF11CYP11B2ARNSD2PDK2 | |
| SCHEMBL2371259 | 0.78 | AR (0.47) | KIF11PTGDR2ARPDK2TRPV4 | |
| SCHEMBL13063632 | 0.78 | KIF11 (1.00) | KIF11PTGDR2DGAT1SOAT1KCNH2 | |
| SCHEMBL3456838 | 0.78 | KIF11 (1.00) | KIF11PTGDR2DGAT1SOAT1KCNH2 | |
| SCHEMBL20111544 | 0.78 | KIF11 (0.43) | KIF11PTGDR2DGAT1SOAT1KCNH2 | |
| SCHEMBL20111587 | 0.78 | ALOX5AP (0.47) | KIF11CYP11B2ARALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067638-B2 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2011-11-29 | — | — | US | disclosed |