SCHEMBL13609752

SCHEMBL13609752

C=C(C)C(=O)OCCOC(=O)c1cc2ccc(N(CC)CC)cc2oc1=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.72
MEN1 O00255 7/20 0.65
MAPT P10636 7/20 0.65
KMT2A Q03164 7/20 0.65
ATM Q13315 3/20 0.65
USP2 O75604 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP2C19 P33261 1/20 0.65
ALDH1A1 P00352 8/20 0.61
KDM4E B2RXH2 8/20 0.61
HPGD P15428 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
HSD17B10 Q99714 2/20 0.61
SLC16A3 O15427 1/20 0.61
ALOX15 P16050 1/20 0.61
SLC16A1 P53985 1/20 0.61
CYP19A1 P11511 2/20 0.52
NPC1 O15118 1/20 0.52
STAT3 P40763 1/20 0.52
STAT1 P42224 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7734217 0.95 MAOB (0.69) MAOBMEN1MAPTKMT2AATM
SCHEMBL9302603 0.87 KMT2A (0.61) MAOBMEN1MAPTKMT2AATM
SCHEMBL4598366 0.86 MAOB (0.80) MAOBMEN1MAPTKMT2AATM
SCHEMBL17597644 0.85 MAOB (0.79) MAOBMEN1MAPTKMT2AATM
SCHEMBL1772718 0.84 MAOB (1.00) MAOBMEN1MAPTKMT2AATM
SCHEMBL29816856 0.84 MAOB (0.80) MAOBMEN1MAPTKMT2AATM
SCHEMBL22923741 0.83 MAOB (0.72) MAOBMEN1MAPTKMT2AATM
SCHEMBL13432119 0.83 MAOB (0.76) MAOBMEN1MAPTKMT2AATM
SCHEMBL13840825 0.83 MAOB (0.76) MAOBMEN1MAPTKMT2AATM
SCHEMBL14753531 0.83 KDM4E (0.51) MAOBMEN1MAPTKMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9389182-B2 Labeling of proteins with the fluorophore 7-amino-4-methylcoumarin (AMC) generated novel proteolytic substrates UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2016-07-12 US disclosed
US-9389182-B2 Labeling of proteins with the fluorophore 7-amino-4-methylcoumarin (AMC) generated novel proteolytic substrates UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2016-07-12 US disclosed
US-20130059321-A1 Labeling of Proteins with the Fluorophore 7-amino-4-methylcoumarin (AMC) Generated Novel Proteolytic Substrates UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-03-07 US disclosed
US-20130059321-A1 Labeling of Proteins with the Fluorophore 7-amino-4-methylcoumarin (AMC) Generated Novel Proteolytic Substrates UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-03-07 US disclosed
US-8338529-B2 Oil repellent copolymer, method for its production and oil repellent treatment solution ASAHI GLASS COMPANY, LIMITED (JP) 2012-12-25 US disclosed
US-8338529-B2 Oil repellent copolymer, method for its production and oil repellent treatment solution ASAHI GLASS COMPANY, LIMITED (JP) 2012-12-25 US disclosed
US-20090281239-A1 OIL REPELLENT COPOLYMER, METHOD FOR ITS PRODUCTION AND OIL REPELLENT TREATMENT SOLUTION ASAHI GLASS COMPANY LIMITED (JP) 2009-11-12 US disclosed
US-20090281239-A1 OIL REPELLENT COPOLYMER, METHOD FOR ITS PRODUCTION AND OIL REPELLENT TREATMENT SOLUTION ASAHI GLASS COMPANY LIMITED (JP) 2009-11-12 US disclosed