SCHEMBL1360982

SCHEMBL1360982

O=CC12CC3SC(C1)SC(C2)S3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8679383 0.71
Ammonia Solution, Strong SCHEMBL11787417 0.65 NPFFR1 (0.37)
SCHEMBL12138553 0.58
SCHEMBL2414202 0.57 NPFFR1 (0.31)
SCHEMBL1361570 0.57 GRM4 (0.32)
SCHEMBL6235140 0.57
SCHEMBL2362307 0.55
SCHEMBL11787902 0.54
SCHEMBL14116852 0.50
SCHEMBL12280437 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7501529-B2 7-Ethynyl-2,4,9-trithiaadamantane and related methods THE UNIVERSITY OF AKRON (US) 2009-03-10 US claimed
US-20080177094-A1 7-Ethynyl-2,4,9-Trithiaadamantane and Related Methods AKRON, THE UNIVERSITY OF 2008-07-24 US claimed
WO-2005003089-A2 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2005-01-13 WO claimed
US-8066914-B2 7-ethynyl-2,4,9-trithiaadamantane and related methods UNIVERSITY OF AKRON (US) 2011-11-29 US disclosed
US-8066914-B2 7-ethynyl-2,4,9-trithiaadamantane and related methods UNIVERSITY OF AKRON (US) 2011-11-29 US disclosed
US-8066914-B2 7-ethynyl-2,4,9-trithiaadamantane and related methods UNIVERSITY OF AKRON (US) 2011-11-29 US disclosed
US-8066914-B2 7-ethynyl-2,4,9-trithiaadamantane and related methods UNIVERSITY OF AKRON (US) 2011-11-29 US disclosed
US-20100072425-A1 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2010-03-25 US disclosed
US-20100072425-A1 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2010-03-25 US disclosed
US-20100072425-A1 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2010-03-25 US disclosed
US-20100072425-A1 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2010-03-25 US disclosed
US-7501529-B2 7-Ethynyl-2,4,9-trithiaadamantane and related methods THE UNIVERSITY OF AKRON (US) 2009-03-10 US disclosed
US-7501529-B2 7-Ethynyl-2,4,9-trithiaadamantane and related methods THE UNIVERSITY OF AKRON (US) 2009-03-10 US disclosed
US-20080177094-A1 7-Ethynyl-2,4,9-Trithiaadamantane and Related Methods AKRON, THE UNIVERSITY OF 2008-07-24 US disclosed
US-20080177094-A1 7-Ethynyl-2,4,9-Trithiaadamantane and Related Methods AKRON, THE UNIVERSITY OF 2008-07-24 US disclosed
US-20080177094-A1 7-Ethynyl-2,4,9-Trithiaadamantane and Related Methods AKRON, THE UNIVERSITY OF 2008-07-24 US disclosed
US-20080177094-A1 7-Ethynyl-2,4,9-Trithiaadamantane and Related Methods AKRON, THE UNIVERSITY OF 2008-07-24 US disclosed
WO-2005003089-A3 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS UNIV AKRON (US) 2005-09-29 WO disclosed
WO-2005003089-A2 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2005-01-13 WO disclosed
WO-2005003089-A2 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS THE UNIVERSITY OF AKRON (US) 2005-01-13 WO disclosed