Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717720 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29705738 | 0.71 | — | — | |
| SCHEMBL1360418 | 0.70 | NPSR1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL18710972 | 0.70 | — | — | |
| SCHEMBL12714 | 0.69 | HSD11B1 (0.48) | ALDH1A1CYP2C9KDM4E | |
| SCHEMBL19557168 | 0.69 | HSD11B1 (0.48) | ALDH1A1CYP2C9KDM4E | |
| SCHEMBL19557166 | 0.69 | HSD11B1 (0.48) | ALDH1A1CYP2C9KDM4E | |
| SCHEMBL5489940 | 0.67 | HSD11B1 (0.46) | ALDH1A1CYP2C9KDM4E | |
| SCHEMBL5487136 | 0.67 | HSD11B1 (0.46) | ALDH1A1CYP2C9KDM4E | |
| SCHEMBL4389277 | 0.67 | HSD11B1 (0.46) | ALDH1A1CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003089-A2 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | THE UNIVERSITY OF AKRON (US) | 2005-01-13 | — | — | WO | claimed |
| US-8066914-B2 | 7-ethynyl-2,4,9-trithiaadamantane and related methods | UNIVERSITY OF AKRON (US) | 2011-11-29 | — | — | US | disclosed |
| US-8066914-B2 | 7-ethynyl-2,4,9-trithiaadamantane and related methods | UNIVERSITY OF AKRON (US) | 2011-11-29 | — | — | US | disclosed |
| US-8066914-B2 | 7-ethynyl-2,4,9-trithiaadamantane and related methods | UNIVERSITY OF AKRON (US) | 2011-11-29 | — | — | US | disclosed |
| US-7777476-B2 | Dynamic modulation for multiplexation of microfluidic and nanofluidic based biosensors | THE UNIVERSITY OF AKRON (US) | 2010-08-17 | — | — | US | disclosed |
| US-7777476-B2 | Dynamic modulation for multiplexation of microfluidic and nanofluidic based biosensors | THE UNIVERSITY OF AKRON (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100072425-A1 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | THE UNIVERSITY OF AKRON (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100072425-A1 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | THE UNIVERSITY OF AKRON (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100072425-A1 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | THE UNIVERSITY OF AKRON (US) | 2010-03-25 | — | — | US | disclosed |
| US-20090066315-A1 | DYNAMIC MODULATION FOR MULTIPLEXATION OF MICROFLUIDIC AND NANOFLUIDIC BASED BIOSENSORS | THE UNIVERSITY OF AKRON (US) | 2009-03-12 | — | — | US | disclosed |
| US-7348441-B2 | Methyl 2,4,9-trithiaadamantane-7-carboxylate | THE UNIVERSITY OF AKRON (US) | 2008-03-25 | — | — | US | disclosed |
| WO-2005120186-A3 | METHYL 2,4,9-TRITHIAADAMANTANE-7-CARBOXYLATE | UNIV AKRON (US) | 2007-08-16 | — | — | WO | disclosed |
| US-20070173650-A1 | Methyl 2,4,9-trithiaadamantane-7-carboxylate | UNIVERSITY OF AKRON | 2007-07-26 | — | — | US | disclosed |
| EP-1740592-A2 | METHYL 2,4,9-TRITHIAADAMANTANE-7-CARBOXYLATE | THE UNIVERSITY OF AKRON (US) | 2007-01-10 | — | — | EP | disclosed |
| EP-1740592-A2 | METHYL 2,4,9-TRITHIAADAMANTANE-7-CARBOXYLATE | THE UNIVERSITY OF AKRON (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005120186-A2 | METHYL 2,4,9-TRITHIAADAMANTANE-7-CARBOXYLATE | THE UNIVERSITY OF AKRON (US) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005120186-A2 | METHYL 2,4,9-TRITHIAADAMANTANE-7-CARBOXYLATE | THE UNIVERSITY OF AKRON (US) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005003089-A3 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | UNIV AKRON (US) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005003089-A2 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | THE UNIVERSITY OF AKRON (US) | 2005-01-13 | — | — | WO | disclosed |
| WO-2005003089-A2 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | THE UNIVERSITY OF AKRON (US) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100072425-A1 | 7-ETHYNYL-2,4,9-TRITHIAADAMANTANE AND RELATED METHODS | ALKBH2, AOX1, TET1 | GRM4 1088/4885CYP2C19 1550/4885ALDH1A1 12/4885 |
| US-20070173650-A1 | Methyl 2,4,9-trithiaadamantane-7-carboxylate | TST, TPMT, MGMT | GRM4 235/4885CYP2C19 3515/4885ALDH1A1 182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.