Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 10/20 | 0.58 |
| ▸ | RARG | P13631 | 10/20 | 0.58 |
| ▸ | RARA | P10276 | 10/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | GOT1 | P17174 | 1/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7929420 | 0.99 | MEN1 (0.57) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7929371 | 0.93 | RARB (0.51) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7927672 | 0.92 | RARB (0.50) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7929425 | 0.92 | RARB (0.50) | MEN1KMT2ATHRBRECQLNR2E1 | |
| Acetic Acid SCHEMBL7926656 | 0.90 | RARB (0.48) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL6032184 | 0.90 | RARG (0.53) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7926526 | 0.89 | RARB (0.46) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7929996 | 0.89 | RARB (0.47) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7926557 | 0.89 | RARB (0.45) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL1684004 | 0.89 | RARB (0.48) | MEN1KMT2ATHRBRECQLNR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8066976-B2 | Foaming compositions for hair care | GALDERMA S.A. (CH) | 2011-11-29 | — | — | US | claimed |
| US-20100234337-A1 | FOAMING COMPOSITIONS FOR HAIR CARE | GALDERMA S.A. (CH) | 2010-09-16 | — | — | US | claimed |
| US-20100144683-A1 | METHODS FOR GENERATING MAMMALIAN MODELS OF ATOPIC DISEASES, AND SCREENING FOR THEIR TREATMENT | ASSOCIATION POUR LA RECHERCHE A L'IGBMC (ARI) (FR) | 2010-06-10 | — | — | US | claimed |
| EP-2046309-A2 | USE OF VITAMIN D3 AGONIST IN A MAMMALIAN MODEL FOR ATOPIC DISEASES AND OF VITAMIN D3 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DISEASES | Association pour la recherche à l'IGBMC (ARI) (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1891944-A1 | Use of Vitamin D3 agonist in a mammalian model for atopic diseases and of Vitamin D3 antagonists for the treatment of atopic diseases | Association pour la recherche à l'IGBMC (ARI) (FR) | 2008-02-27 | — | — | EP | claimed |
| WO-2008012645-A2 | USE OF VITAMIN D3 AGONIST IN A MAMMALIAN MODEL FOR ATOPIC DISEASES AND OF VITAMIN D3 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DISEASES | ASSOCIATION POUR LA RECHERCHE A L'IGBMC (ARI) (FR) | 2008-01-31 | — | — | WO | claimed |
| EP-1087747-B1 | FOAMING COMPOSITION FOR HAIR CARE | GALDERMA SA (CH) | 2005-11-09 | — | — | EP | claimed |
| EP-0874626-B1 | USE OF INHIBITORS OF RETINOIC ACID ACTIVITY FOR WOUND HEALING | CT INTERNAT DERECH S DERMATOLO (FR) | 2004-12-29 | — | — | EP | claimed |
| EP-0892633-B1 | USE OF INHIBITORS OF THE ACTIVITY OF RETINOIC ACID FOR TREATING SENSITIVE SKIN AND/OR ACUTE DAMAGE INDUCED BY UV RADIATION | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-03-05 | — | — | EP | claimed |
| EP-0854711-B1 | gamma-RAR ANTAGONIST LIGAND OR alpha-RAR AGONIST LIGAND AS AN APOPTOSIS INHIBITOR | GALDERMA RECH DERMATOLOGIQUE (FR) | 2002-01-23 | — | — | EP | claimed |
| US-6248749-B1 | TOPICALLY APPLYING RETINOID ANTAGONIST TO SENSITIVE SKIN TO TREAT ALLERGIES/SUNBURN | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2001-06-19 | — | — | US | claimed |
| US-6063797-A | γ-RAR antagonist ligand or α-RAR agonist ligand as an apoptosis inhibitor | C.I.R.D. GALDERMA (FR) | 2000-05-16 | — | — | US | claimed |
| US-5973007-A | SURGERY, TRAUMA WOUNDS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-10-26 | — | — | US | claimed |
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | claimed |
| EP-0740937-A2 | Use of retinoids for the manufacture of a pharmaceutical or cosmetic composition | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1996-11-06 | — | — | EP | claimed |
| US-8066976-B2 | Foaming compositions for hair care | GALDERMA S.A. (CH) | 2011-11-29 | — | — | US | disclosed |
| US-8066975-B2 | Psoriasis or seborrheic dermatitis; mixture of clobetasol propionate, an anionic surfactant (sodium lauryl ether sulfate), an amphoteric surfactant ( cocamidopropyl betaines); a propenetrating agent chosen from ethanol, isopropanol, propylene glycol and ethoxydiglycol; foam with good compactnes; shampoo | GALDERMA S.A. (CH) | 2011-11-29 | — | — | US | disclosed |
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | disclosed |
| EP-0740937-A2 | Use of retinoids for the manufacture of a pharmaceutical or cosmetic composition | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1996-11-06 | — | — | EP | disclosed |
| EP-0658553-A1 | Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234337-A1 | FOAMING COMPOSITIONS FOR HAIR CARE | RARA, NR5A1, SHH | MEN1 2113/4885KMT2A 4554/4885THRB 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.