SCHEMBL13610220

SCHEMBL13610220

CCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(=O)c1csc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.64
TSHR P16473 6/20 0.64
LMNA P02545 3/20 0.64
MAPK1 P28482 4/20 0.61
CYP3A4 P08684 3/20 0.61
TP53 P04637 1/20 0.61
KDM4E B2RXH2 5/20 0.57
HSD17B10 Q99714 2/20 0.57
POLB P06746 1/20 0.57
L3MBTL1 Q9Y468 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.52
KDM4A O75164 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11814952 0.85 HDAC3 (0.56) ALDH1A1TSHRLMNACYP3A4TP53
SCHEMBL20061727 0.82 SCN1A (0.45) ALDH1A1TSHRLMNAMAPK1CYP3A4
Ethylene SCHEMBL27870627 0.79 ALDH1A1 (0.93) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL14891680 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL5072881 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL3212303 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL7219181 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL2527136 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL4210493 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4
SCHEMBL8609367 0.79 ALDH1A1 (1.00) ALDH1A1TSHRLMNAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US disclosed
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US disclosed