Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927281 | 0.89 | TAAR1 (0.58) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL19592249 | 0.85 | TAAR1 (0.55) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL4268169 | 0.85 | TAAR1 (0.55) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL25464586 | 0.83 | EPHX1 (0.50) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL23927275 | 0.81 | TAAR1 (0.58) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL1145952 | 0.78 | HTR2A (0.56) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL1145949 | 0.78 | TAAR1 (0.55) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL25464631 | 0.76 | EPHX1 (0.50) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL7519147 | 0.75 | HTR2A (0.53) | TAAR1EPHX1IDO1HTR2AHTR2C | |
| SCHEMBL29460217 | 0.75 | TAAR1 (0.60) | TAAR1IDO1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622507-B2 | Substituted organosulfur compounds and methods of using thereof | ACEA BIOSCIENCES INC. (US) | 2009-11-24 | — | — | US | disclosed |