Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927275 | 0.89 | TAAR1 (0.58) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL13778151 | 0.84 | ACHE (0.39) | HTR2AHTR2BHTR2CEPHX1RAB9A | |
| SCHEMBL25464631 | 0.83 | EPHX1 (0.50) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL1145952 | 0.81 | HTR2A (0.56) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL23927281 | 0.81 | TAAR1 (0.58) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL46757 | 0.81 | HTR2A (0.63) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL20734675 | 0.80 | ACHE (0.46) | TAAR1IDO1LMNARAB9A | |
| SCHEMBL15023045 | 0.79 | TAAR1 (0.62) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| Ammonia Solution, Strong SCHEMBL266843 | 0.79 | HTR2A (0.61) | HTR2AHTR2BHTR2CEPHX1TAAR1 | |
| SCHEMBL14382766 | 0.78 | EPHX1 (0.49) | HTR2AHTR2BHTR2CEPHX1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |