Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209031 | 0.79 | MAOA (0.52) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29927997 | 0.79 | NPC1 (0.53) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3191937 | 0.79 | TLR9 (0.57) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1822333 | 0.79 | MAOA (0.52) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17691569 | 0.79 | MAOA (0.58) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12428927 | 0.79 | CYP1A2 (0.63) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14314827 | 0.78 | MAOA (0.53) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL713218 | 0.77 | CYP1A2 (0.66) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31325779 | 0.77 | CYP1A2 (0.66) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL29085625 | 0.76 | CYP1A2 (0.64) | MAOAMAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315588-B1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | ROTTAPHARM SPA (IT) | 2012-12-19 | — | — | EP | disclosed |
| WO-2009152868-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | ROTTAPHARM S.P.A. (IT) | 2009-12-23 | — | — | WO | disclosed |