Pyridine

Pyridine

SCHEMBL1361154

S.c1ccncc1.c1ccncc1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.90
NAPRT Q6XQN6 1/20 0.90
TDP1 Q9NUW8 1/20 0.90
NOTUM Q6P988 1/20 0.39
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2A6 P11509 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL2845994 1.00
Pyridine SCHEMBL2236054 1.00
Benzene SCHEMBL27363644 1.00 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL730865 1.00 TSHR (0.90) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL8709944 0.95 TSHR (0.82) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL10894137 0.95 TSHR (0.82) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL27402260 0.95
Pyridine SCHEMBL28814972 0.95
Pyridine SCHEMBL27503566 0.95
Pyridine SCHEMBL27618775 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304790-B Water-based environment-friendly paint and water-based leather 石狮佳南热熔胶有限公司 2024-02-09 CN claimed
CN-117304790-A Water-based environment-friendly paint and water-based leather 石狮佳南热熔胶有限公司 2023-12-29 CN claimed
CN-113185700-A Three-dimensional coordination polymer molecular material with high adsorption performance on mercury ions 山东理工大学 2021-07-30 CN claimed
CN-107556489-B Pressure-controlled spin cross molecular magnetic material and preparation method thereof 山东理工大学 2020-06-19 CN claimed
CN-107602626-B three-dimensional spin cross molecular magnetic material and preparation method thereof 山东理工大学 2019-12-13 CN claimed
CN-107602626-A A kind of three-dimensional spin crossover molecular magnetic materialses and preparation method thereof 山东理工大学 2018-01-19 CN claimed
CN-107556489-A A kind of spin crossover molecular magnetic materialses of Stress control and preparation method thereof 山东理工大学 2018-01-09 CN claimed
CN-101376676-B PEGylated erythropoietin protein long-acting preparation TIANJIN PAIGE BIOTECHNOLOGY CO LTD 2012-04-25 CN claimed
CN-101115993-A Use of thiopeptolides for determining the activity of ADAMTS proteases SANOFI AVENTIS (FR) 2008-01-30 CN claimed
CN-1896120-A Preparation of polyarylphenyl resin by phase-transferring catalyst UNIV SICHUAN (CN) 2007-01-17 CN claimed
US-6407245-B2 HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-06-18 US claimed
US-20010012897-A1 Substituted thiopyridines HAMPRECHT GERHARD (DE) 2001-08-09 US claimed
US-6262273-B1 REACTING A3-CHLORO-2-HALOPYRIDINE WITH THIO COMPOUND IN PRESENCE OF TRIFLUOROACETIC ACID OR PERCHLORIC ACID TO GIVE PYRIDINE THIOETHER COMPOUND WHICH IS OXIDIZED TO GIVE THIOPYRIDINE COMPOUND BASF AKTIENGESELLSCHAFT (DE) 2001-07-17 US claimed
US-6191280-B1 REACTING SUBSTITUTED 2-HALOPYRIDINE DERIVATIVE WITH A THIO COMPOUND IN PRESENCE OF COPPER CATALYST TO GIVE A PYRIDINE THIOETHER, AND THEN OXIDIZING THE THIOETHER INTERMEDIATE TO FORM SULFOXIDE OR SULFONE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-02-20 US claimed
CN-1232454-A Substituted Thiopyridines BASF AG (DE) 1999-10-20 CN claimed
CN-115160216-B Hydrazide compound containing pyridine structure and preparation and application thereof 聊城大学 2024-04-19 CN disclosed
CN-117304790-B Water-based environment-friendly paint and water-based leather 石狮佳南热熔胶有限公司 2024-02-09 CN disclosed
US-5703116-A TREATING CANCER GERON CORPORATION (US) 1997-12-30 US disclosed
EP-0764049-A1 ALKALI RESISTANT PROTEIN ADSORBENT OSCARSSON, Sven (SE) 1997-03-26 EP disclosed
WO-1995033557-A1 ALKALI RESISTANT PROTEIN ADSORBENT OSCARSSON SVEN (SE) 1995-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012897-A1 Substituted thiopyridines CBR1, CLIC1, CBR3 TSHR 1666/4885NAPRT 2899/4885TDP1 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.