⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16668528 | 1.00 | — | — | |
| SCHEMBL20648 | 1.00 | — | — | |
| SCHEMBL30438355 | 0.97 | TSHR (0.56) | — | |
| Magnesium SCHEMBL31182158 | 0.97 | — | — | |
| SCHEMBL27612242 | 0.97 | — | — | |
| SCHEMBL28743875 | 0.97 | — | — | |
| SCHEMBL5487434 | 0.97 | — | — | |
| Methyl Alcohol SCHEMBL14861497 | 0.97 | — | — | |
| SCHEMBL28746708 | 0.97 | — | — | |
| SCHEMBL27550531 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187308-A1 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2016-11-24 | — | — | WO | disclosed |
| US-20160192678-A1 | FEED FOR LACTATING RUMINANTS | BENEMILK OY (FI) | 2016-07-07 | — | — | US | disclosed |
| EP-1967516-B1 | 4-(phenylamino)-6-oxo-1,6-dihydropyridazine-3-carboxamide derivatives as MEK inhibitors for the treatment of hyperproliferative diseases | ARRAY BIOPHARMA INC (US) | 2009-11-04 | — | — | EP | disclosed |