SCHEMBL13611672

SCHEMBL13611672

CC1c2ccc(Cl)cc2CCc2cc(Br)cnc21

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.50
FNTB P49356 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5771912 0.84 FNTA (0.51) FNTAFNTB
SCHEMBL13604621 0.83 FNTA (0.51) FNTAFNTB
SCHEMBL13604328 0.83 FNTA (0.50) FNTAFNTB
SCHEMBL14083334 0.80 FNTA (0.48) FNTAFNTB
SCHEMBL13611706 0.77 FNTA (0.58) FNTAFNTB
SCHEMBL18067707 0.77 HTR2C (0.56) FNTAFNTB
SCHEMBL13935176 0.75 FNTA (0.64) FNTAFNTB
SCHEMBL6769971 0.75 FNTA (0.69) FNTAFNTB
SCHEMBL14416063 0.72 FNTA (0.40) FNTAFNTB
SCHEMBL13935172 0.72 FNTA (0.40) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635697-B2 Farnesyl protein transferase inhibitors and methods for treating proliferative diseases SCHERING CORPORATION (US) 2009-12-22 US disclosed
EP-1572299-B1 17 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 INHIBITORS FOR THE TREATMENT OF ANDROGEN DEPENDENT DISEASES SCHERING CORP (US) 2008-09-24 EP disclosed