Sugi Predict

Sugi Predict / Compounds / SCHEMBL13611706

SCHEMBL13611706

SCHEMBL13611706

CC1c2ccc(Cl)cc2CCc2cccnc21

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 8/20 0.58
▸ FNTB P49356 8/20 0.58
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ SLC6A15 Q9H2J7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1978262 0.84 FNTA (0.60) FNTAFNTB
SCHEMBL6176740 0.82 FNTA (0.58) FNTAFNTB
SCHEMBL14289895 0.82 FNTA (0.58) FNTAFNTBSLC6A15
SCHEMBL13604336 0.82 FNTA (0.55) FNTAFNTBSLC6A15
SCHEMBL22193900 0.81 HTR2A (0.39) FNTAFNTB
SCHEMBL8355428 0.81 HTR2A (0.39) FNTAFNTB
SCHEMBL18067707 0.79 HTR2C (0.56) FNTAFNTB
SCHEMBL14288461 0.78 MEN1 (0.56) FNTAFNTBMEN1KMT2AATM
SCHEMBL13611672 0.77 FNTA (0.50) FNTAFNTB
SCHEMBL14102189 0.77 MEN1 (0.58) FNTAFNTBMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635697-B2 Farnesyl protein transferase inhibitors and methods for treating proliferative diseases SCHERING CORPORATION (US) 2009-12-22 — — US disclosed
EP-1318994-B1 SUBSTITUTED IMIDAZOLES AS DUAL HISTAMINE H1 AND H3 AGONISTS OR ANTAGONISTS SCHERING CORP (US) 2008-02-27 — — EP disclosed