Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287311 | 0.88 | ALDH1A1 (0.68) | MEN1KMT2ATBXA2RPPARGALDH1A1 | |
| SCHEMBL8288311 | 0.88 | TAAR1 (0.59) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL8289277 | 0.87 | ALDH1A1 (0.57) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL8287312 | 0.86 | AKR1C3 (0.51) | MEN1KMT2ATBXA2RPRMT1ALDH1A1 | |
| SCHEMBL8288312 | 0.84 | LSS (0.56) | MEN1KMT2ALSSALDH1A1LMNA | |
| SCHEMBL13863246 | 0.84 | ALDH1A1 (0.70) | MEN1KMT2APPARGALDH1A1TP53 | |
| SCHEMBL8289774 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2ATBXA2RALDH1A1TP53 | |
| SCHEMBL9754552 | 0.82 | MEN1 (0.84) | MEN1KMT2ATBXA2RPRMT1PPARG | |
| SCHEMBL13604129 | 0.81 | MEN1 (0.59) | MEN1KMT2ATBXA2RPRMT1PPARG | |
| SCHEMBL8288313 | 0.81 | CA1 (0.42) | KMT2AALDH1A1GAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625932-B2 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| US-20070066573-A1 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066573-A1 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | GRIN1, GRIN3A, GRIK5 | MEN1 4720/4885KMT2A 3400/4885TBXA2R 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.