Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 3/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612509 | 1.00 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL22813825 | 0.91 | NPC1 (0.56) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14606216 | 0.91 | NPC1 (0.49) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14262013 | 0.87 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9325684 | 0.87 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL7587876 | 0.87 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14262015 | 0.87 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL4531460 | 0.87 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL26602072 | 0.86 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13612519 | 0.86 | SMPD1 (0.57) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622432-B2 | Lubricant composition and triazine-ring-containing compound | FUJIFILM CORPORATION (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20090118146-A1 | IMPREGNATING OIL COMPOSITION FOR SINTERED BEARING, BEARING APPARATUS AND SLIDING MEMBER | FUJIFILM CORPORATION (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20080134938-A1 | Surface Treatment Method Employing Discotic Compound, (Lubricant) Composition to Be Used Surface Treatments, and Surface-Treated Articles | FUJIFILM CORPORATION (JP) | 2008-06-12 | — | — | US | disclosed |