Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.63 |
| ▸ | RELA | Q04206 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.60 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325684 | 1.00 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14262015 | 1.00 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL4531460 | 1.00 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14262013 | 1.00 | NPC1 (0.63) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL14363608 | 0.87 | NPC1 (0.61) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13612503 | 0.87 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13612509 | 0.87 | NPC1 (0.57) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9403669 | 0.86 | NPC1 (0.81) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL21084422 | 0.86 | NPC1 (0.81) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL22341180 | 0.86 | NPC1 (0.81) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9059410-B2 | Liquid crystalline organic semiconductor material and organic semiconductor device using same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20080058544-A1 | Liquid crystalline organic semiconductor material and organic semiconductor device using same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-03-06 | — | — | US | disclosed |
| EP-0656559-B1 | Optical compensatory sheet | FUJI PHOTO FILM CO LTD (JP) | 2002-10-16 | — | — | EP | disclosed |
| US-5736067-A | SHEET COMPRISING LAYER IN CONDITION OF MONO-DOMAIN OF DISCOTIC NEMATIC PHASE, OPTIC AXIS OF SHEET INCLINED AT 5 TO 50 DEGREES FROM LINE NORMAL TO SHEET | FUJI PHOTO FILM CO, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| US-5518783-A | TRANSPARENT SUPPORT HAVING OPTIC AXIS INCLINED AT SPECIFIED ANGLE TO NORMAL, OPTICALLY ANISOTROPIC LAYER FORMED FROM DISCOTIC COMPOUND AND COMPATIBLE COMPOUND WHICH LOWERS TRANSITION TEMPERATURE | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0676652-A2 | Optical compensatory sheet and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0656559-A1 | Optical compensatory sheet and process for preparation of the same and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058544-A1 | Liquid crystalline organic semiconductor material and organic semiconductor device using same | SLCO4C1, SLCO2A1, SLCO1A2 | NPC1 376/4885LMNA 2564/4885NFKB1 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.