Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.45 |
| ▸ | C5 | P01031 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555432 | 0.95 | DGKA (0.44) | SMPD1CNR2EPHX2 | |
| SCHEMBL13612602 | 0.82 | MAPT (0.40) | SMPD1C5 | |
| SCHEMBL14566061 | 0.80 | CNR2 (0.52) | SMPD1THRATHRBCNR2 | |
| SCHEMBL7045169 | 0.79 | MAPT (0.44) | SMPD1C5 | |
| SCHEMBL7046869 | 0.79 | MAPT (0.44) | SMPD1C5 | |
| SCHEMBL13612601 | 0.79 | MAPT (0.44) | SMPD1C5 | |
| SCHEMBL13854957 | 0.77 | DGKA (0.51) | THRATHRBCNR2 | |
| SCHEMBL14163925 | 0.77 | DGKA (0.51) | THRATHRBCNR2 | |
| SCHEMBL13612597 | 0.76 | DGKA (0.50) | SMPD1CNR2 | |
| SCHEMBL13933063 | 0.76 | DGKA (0.50) | SMPD1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622432-B2 | Lubricant composition and triazine-ring-containing compound | FUJIFILM CORPORATION (JP) | 2009-11-24 | — | — | US | disclosed |