Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27592978 | 0.83 | KDM4E (0.47) | KDM4ECASP6LMNAPOLBNQO2 | |
| SCHEMBL28038623 | 0.83 | KDM4E (0.47) | KDM4ECASP6LMNAPOLBNQO2 | |
| Hydrochloric Acid SCHEMBL3761973 | 0.82 | KDM4E (0.46) | KDM4ECASP6LMNAPOLBNQO2 | |
| SCHEMBL12258269 | 0.78 | CYP1A2 (0.46) | KDM4ELMNANQO2CYP2A6ALDH1A1 | |
| SCHEMBL28328278 | 0.75 | GAA (0.41) | KDM4ELMNAPOLBALDH1A1HSD17B10 | |
| SCHEMBL27251840 | 0.75 | MPO (0.42) | KDM4ELMNACYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL15933155 | 0.75 | POLB (0.53) | KDM4EPOLBALDH1A1NR4A2HSD17B10 | |
| SCHEMBL14970173 | 0.75 | MPO (0.42) | KDM4ECYP2A6SMN1; SMN2MAPT | |
| SCHEMBL1104999 | 0.73 | CYP2A6 (0.53) | KDM4ECASP6LMNAPOLBPLAU | |
| SCHEMBL803413 | 0.72 | NR1I2 (0.41) | KDM4ELMNAPOLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443080-B | There is the sulfonamide compounds of TRPM8 antagonistic activity | 田边三菱制药株式会社 | 2016-10-12 | — | — | CN | disclosed |
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |