Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916156 | 0.85 | RIPK1 (0.45) | LMNARIPK1 | |
| SCHEMBL2910772 | 0.84 | MEN1 (0.43) | MEN1KMT2ATSHRNR1H2LMNA | |
| SCHEMBL2910770 | 0.84 | MEN1 (0.43) | MEN1KMT2ATSHRNR1H2LMNA | |
| SCHEMBL2914617 | 0.84 | MEN1 (0.43) | MEN1KMT2ATSHRNR1H2LMNA | |
| SCHEMBL23064495 | 0.82 | RIPK1 (0.44) | MEN1KMT2ATSHRNR1H2LMNA | |
| SCHEMBL26838484 | 0.82 | RIPK1 (0.44) | MEN1KMT2ATSHRNR1H2LMNA | |
| SCHEMBL20170496 | 0.81 | HSP90AA1 (0.56) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL22165572 | 0.80 | RIPK1 (0.47) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL23579324 | 0.80 | RIPK1 (0.47) | MEN1KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL29748129 | 0.80 | RIPK1 (0.47) | MEN1KMT2ATSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |