SCHEMBL13613477

SCHEMBL13613477

COC(=O)[C@H]1CCN[C@@H]1c1cc(NC(C)=O)ccc1S(=O)(=O)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.40
F7 P08709 14/20 0.37
F3 P13726 14/20 0.37
ALDH1A1 P00352 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
INSR P06213 1/20 0.35
ALK Q9UM73 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13613443 1.00 CDK1 (0.40) CDK1F7F3ALDH1A1CHRNB2
SCHEMBL13613444 1.00 CDK1 (0.40) CDK1F7F3ALDH1A1CHRNB2
Trifluoroacetic Acid SCHEMBL2914337 0.94 F7 (0.36) CDK1F7F3ALDH1A1CHRNB2
Trifluoroacetic Acid SCHEMBL2914335 0.94 F7 (0.36) CDK1F7F3ALDH1A1CHRNB2
SCHEMBL11348081 0.92 F7 (0.43) F7F3
SCHEMBL13613521 0.92 F7 (0.43) F7F3
SCHEMBL2914356 0.88 F7 (0.34) CDK1F7F3ALDH1A1CHRNB2
Trifluoroacetic Acid SCHEMBL2914351 0.84 F7 (0.37) CDK1F7F3ALDH1A1CHRNB2
SCHEMBL13613432 0.84 SLC6A3 (0.35) F7F3ALK
Hydrochloric Acid SCHEMBL2912239 0.83 SLC6A3 (0.35) F7F3ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622585-B2 Phenylglycinamide derivatives useful as anticoagulants BRISTOL-MYERS SQUIBB COMPANY (US) 2009-11-24 US disclosed