Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347961 | 1.00 | PKM (0.43) | PKMMAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11347964 | 1.00 | PKM (0.43) | PKMMAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL13613628 | 0.87 | PKM (0.46) | PKMMAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL13613427 | 0.87 | CDK7 (0.37) | SLC6A2SLC6A3SLC6A4ALKCYP2C19 | |
| SCHEMBL13613512 | 0.87 | CDK7 (0.37) | SLC6A2SLC6A3SLC6A4ALKCYP2C19 | |
| SCHEMBL13613511 | 0.87 | CDK7 (0.37) | SLC6A2SLC6A3SLC6A4ALKCYP2C19 | |
| SCHEMBL8225004 | 0.85 | PKM (0.44) | PKMMAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8221416 | 0.85 | PKM (0.44) | PKMMAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8226803 | 0.85 | PKM (0.44) | PKMMAPTSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8263932 | 0.85 | PKM (0.44) | PKMMAPTSLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |