Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613800 | 0.89 | TLR7 (0.59) | TLR7TLR8 | |
| SCHEMBL13613796 | 0.86 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL13613795 | 0.86 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL5745601 | 0.84 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL5739812 | 0.83 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL13613794 | 0.83 | TLR7 (0.59) | TLR7TLR8 | |
| SCHEMBL13613835 | 0.82 | KMT2A (0.46) | TLR7MEN1KMT2A | |
| SCHEMBL13613793 | 0.82 | TLR7 (0.58) | TLR7TLR8 | |
| SCHEMBL26352210 | 0.81 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL6704858 | 0.81 | TLR7 (0.63) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612083-B2 | Urea substituted imidazoquinoline ethers | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612083-B2 | Urea substituted imidazoquinoline ethers | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7214675-B2 | Urea substituted imidazoquinoline ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214675-B2 | Urea substituted imidazoquinoline ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-08 | — | — | US | disclosed |