Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.50 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | CHAT | P28329 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596519 | 0.87 | HDAC8 (0.62) | KCNH2HDAC8CHATACHE | |
| SCHEMBL9445826 | 0.82 | GRM5 (0.64) | KCNH2GRM5CA12CA2CA9 | |
| SCHEMBL4457730 | 0.82 | GRM5 (0.64) | KCNH2GRM5CA12CA2CA9 | |
| SCHEMBL13614027 | 0.79 | APP (0.64) | KCNH2HDAC8CHATACHE | |
| SCHEMBL13614111 | 0.79 | HDAC8 (0.61) | KCNH2HDAC8CHATALDH1A1CYP2A6 | |
| SCHEMBL13614108 | 0.79 | HDAC8 (0.61) | KCNH2HDAC8GRM5CHATCYP2A6 | |
| SCHEMBL13614028 | 0.79 | APP (0.52) | KCNH2HDAC8CHATCA12CA2 | |
| SCHEMBL9715647 | 0.79 | GRM5 (0.61) | KCNH2GRM5CA12CA2CA9 | |
| SCHEMBL4067660 | 0.78 | APP (0.60) | KCNH2HDAC8GRM5CHATALDH1A1 | |
| SCHEMBL13614029 | 0.77 | CYP2A6 (0.50) | KCNH2HDAC8CHATALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611546-B2 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-7611546-B2 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-20090064423-A1 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-03-12 | — | — | US | disclosed |
| US-20090064423-A1 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | L'OREAL S.A. (FR) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090064423-A1 | Composition comprising at least one substituted acetylenic carbocyanin derivative, process for treating keratin fibres using it, and device therefor | KRT18, HADHB, KAT7 | KCNH2 822/4885HDAC8 608/4885GRM5 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.