Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445826 | 1.00 | GRM5 (0.64) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL9715647 | 0.97 | GRM5 (0.61) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL15014207 | 0.88 | APP (0.67) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL2831992 | 0.88 | APP (0.67) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL10091202 | 0.88 | APP (0.67) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL5012559 | 0.87 | ALDH1A1 (0.52) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL10035462 | 0.86 | ALDH1A1 (0.68) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL12246439 | 0.86 | KCNH2 (0.54) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL21564900 | 0.86 | GRM5 (0.52) | GRM5CA2CA9CA12CA1 | |
| SCHEMBL10035461 | 0.86 | APP (0.74) | GRM5CA2CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285454-A | Synthesis method of indole derivative and benzodipyrrole derivative | 南京邮电大学 | 2023-12-26 | — | — | CN | claimed |
| CN-114560761-B | Method for one-time synthesis of 2,3-disubstituted indanone derivative in aqueous phase | 南京林业大学 | 2023-02-24 | — | — | CN | claimed |
| CN-110028394-B | Synthetic method of indanone and derivatives thereof | 南京邮电大学 | 2021-09-17 | — | — | CN | claimed |
| CN-119505932-A | Preparation method of diphenylacetylene liquid crystal compound containing terminal alkene | 江苏和成新材料有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119192123-A | Preparation method of polysubstituted isocoumarin compound | 厦门医学院 | 2024-12-27 | — | — | CN | disclosed |
| CN-118420533-A | Method for synthesizing isoquinolinone by carbonylation of aryl alkyne and hydroxylamine | 中国科学技术大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-118324603-A | Method for synthesizing chrysene derivatives through palladium-catalyzed cycloaromatization reaction | 湖南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-117964529-A | Method for synthesizing E-alkenyl thioether compound | 江苏海洋大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117945820-A | Method for synthesizing alpha, beta-unsaturated aldehyde compound by copper catalysis | 江苏海洋大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117924191-A | Polysubstituted olefin derivative and preparation method and application thereof | 杭州师范大学 | 2024-04-26 | — | — | CN | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| EP-0006130-B1 | PROCESS FOR THE CATALYTIC PREPARATION OF POLYMERS OR COPOLYMERS OF ALPHA-OLEFINS HAVING A HIGH ISOTACTICITY INDEX, AND COMPOSITION BASED ON TITANIUM CHLORIDE SUITABLE AS COMPONENT OF THE CATALYTIC SYSTEMS USED IN THIS PROCESS | ATO CHIMIE (FR) | 1982-12-08 | — | — | EP | disclosed |
| US-4287093-A | BY USING A CATALYST MADE FROM TITANIUM TRICHLORIDE OR TETRACHLORIDE AND AN ORGANOALUMINUM COMPOUND, AND CONTAINING A CROWN COMPOUND AS A STEREOSPECIFICITY ADDITIVE | ATO CHIMIE (FR) | 1981-09-01 | — | — | US | disclosed |
| US-4259208-A | STEREOSPECIFICITY ADDITIVE CONTAINING SULFIDE AND ETHER LINKAGES | ATO CHEMIE (FR) | 1981-03-31 | — | — | US | disclosed |
| US-4228252-A | STEREOSPECIFIC ADDITIVE OF A SULFIDE AND ETHER COMPOUND | ATO CHIMIE (FR) | 1980-10-14 | — | — | US | disclosed |
| US-4228253-A | STEREOSPECIFIC CROWN ETHER ADDITIVE AND AN ACTIVATOR HAVE A SYNERGISTIC EFFECT | ATO CHIMIE (FR) | 1980-10-14 | — | — | US | disclosed |
| EP-0006130-A1 | Process for the catalytic preparation of polymers or copolymers of alpha-olefins having a high isotacticity index, and composition based on titanium chloride suitable as component of the catalytic systems used in this process | ATO CHIMIE (FR) | 1980-01-09 | — | — | EP | disclosed |
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-4014644-A | OPTICAL BRIGHTENERS FOR POLYAMIDES AND CELLULOSE | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | GRM5 3081/4885CA2 1678/4885CA9 1715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.