Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13544593 | 1.00 | TAAR1 (0.53) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL12517126 | 1.00 | TAAR1 (0.53) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL13544599 | 0.92 | TAAR1 (0.44) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL29315250 | 0.84 | GRM4 (0.46) | TAAR1SMN1; SMN2 | |
| SCHEMBL13544860 | 0.84 | CTSB (0.44) | TAAR1SMN1; SMN2KDM4EHTT | |
| SCHEMBL15430652 | 0.83 | TAAR1 (0.56) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL10173738 | 0.82 | POLB (0.58) | TAAR1HSD17B10ALDH1A1CASP1 | |
| SCHEMBL27000233 | 0.81 | GRM4 (0.56) | TAAR1SMN1; SMN2HSD17B10ALDH1A1CASP1 | |
| SCHEMBL12650951 | 0.80 | POLB (0.65) | TAAR1 | |
| SCHEMBL13753925 | 0.80 | EPHX1 (0.55) | SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |