Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060315 | 0.87 | GAA (0.80) | GAAMAPTBCHEKDM4EALDH1A1 | |
| SCHEMBL17832904 | 0.85 | HRH4 (0.48) | HRH4MEN1KMT2AATMTDP1 | |
| SCHEMBL10133040 | 0.85 | GAA (0.77) | GAAMAPTBCHEKDM4EALDH1A1 | |
| SCHEMBL11881258 | 0.81 | GAA (0.91) | GAAMAPTBCHEKDM4EALDH1A1 | |
| SCHEMBL3272134 | 0.81 | GAA (0.91) | GAAMAPTBCHEKDM4EALDH1A1 | |
| SCHEMBL27228 | 0.79 | GAA (0.95) | GAAMAPTBCHEKDM4EALDH1A1 | |
| SCHEMBL23838671 | 0.79 | HRH4 (0.47) | HRH4MEN1KMT2AATMTDP1 | |
| SCHEMBL13960326 | 0.79 | BCHE (0.70) | GAAMAPTBCHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1983401 | 0.77 | GAA (1.00) | GAAMAPTBCHEKDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL23581968 | 0.77 | GAA (0.91) | GAAMAPTBCHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |