Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435705 | 1.00 | PDE2A (0.53) | PDE2ACA1CA2TDP1CA12 | |
| SCHEMBL27711819 | 0.82 | LOXL2 (0.43) | PDE2ATSHRMAPTRAB9AALDH1A1 | |
| SCHEMBL19435769 | 0.81 | PDE2A (0.53) | PDE2ATDP1MAPTRAB9AL3MBTL1 | |
| SCHEMBL26226803 | 0.80 | MAPT (0.42) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL25214472 | 0.79 | PDE2A (0.51) | PDE2ACA1CA2CA9MAPT | |
| SCHEMBL25246021 | 0.78 | MAPK1 (0.49) | PDE2ACA1CA2TDP1CA12 | |
| SCHEMBL29022617 | 0.78 | CA1 (0.40) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL31470004 | 0.77 | PDE2A (0.56) | PDE2ACA1CA2CA12CA7 | |
| SCHEMBL26227724 | 0.77 | NPC1 (0.43) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL25222349 | 0.76 | DPP4 (0.39) | PDE2ACA1CA2TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612060-B2 | Triazoles and methods of use | AMGEN INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612060-B2 | Triazoles and methods of use | AMGEN INC. (US) | 2009-11-03 | — | — | US | disclosed |