Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 12/20 | 0.44 |
| ▸ | GCGR | P47871 | 3/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430463 | 0.88 | PTGDR2 (0.60) | PTGDR2DDR1GCGRFFAR4 | |
| SCHEMBL2102803 | 0.80 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL12086397 | 0.78 | ABCB11 (0.46) | PTGDR2DDR1GCGRFFAR4 | |
| SCHEMBL5426703 | 0.78 | ABCB11 (0.59) | PTGDR2GCGRFFAR4 | |
| SCHEMBL2099206 | 0.76 | ABCB11 (0.64) | PTGDR2 | |
| SCHEMBL3838842 | 0.76 | PTGDR2 (0.46) | PTGDR2DDR1CCR2 | |
| SCHEMBL15532382 | 0.73 | POLQ (0.52) | FFAR4 | |
| SCHEMBL5428360 | 0.73 | PTGDR2 (0.45) | PTGDR2GCGRFFAR4 | |
| SCHEMBL2394438 | 0.71 | PTGDR2 (0.57) | PTGDR2CCR2FFAR4 | |
| SCHEMBL12257959 | 0.71 | PTGDR2 (0.50) | PTGDR2DDR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784388-B1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2009-11-04 | — | — | EP | disclosed |