⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487376 | 0.75 | — | — | |
| SCHEMBL9018641 | 0.74 | — | — | |
| SCHEMBL31183092 | 0.73 | — | — | |
| SCHEMBL8309556 | 0.70 | — | — | |
| SCHEMBL23850518 | 0.69 | — | — | |
| SCHEMBL3160423 | 0.65 | — | — | |
| SCHEMBL7682580 | 0.62 | — | — | |
| SCHEMBL5242459 | 0.62 | — | — | |
| SCHEMBL28863643 | 0.62 | — | — | |
| SCHEMBL302005 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303851-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. Lundbeck A/S (DK) | 2011-04-06 | — | — | EP | claimed |
| WO-2009156458-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-30 | — | — | WO | claimed |
| US-8067410-B2 | Phenolic and catecholic amines and prodrugs thereof | H. LUNDBECK A/S (DK) | 2011-11-29 | — | — | US | disclosed |
| EP-2303851-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. Lundbeck A/S (DK) | 2011-04-06 | — | — | EP | disclosed |
| US-20090325946-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-31 | — | — | US | disclosed |
| WO-2009156458-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-30 | — | — | WO | disclosed |
| US-5610174-A | Use of α1A -selective adrenoceptor agonists for the treatment of urinary incontinence | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |