⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8122291 | 0.98 | — | — | |
| SCHEMBL28326572 | 0.88 | — | — | |
| SCHEMBL643818 | 0.88 | — | — | |
| Cyclohexanone SCHEMBL28357381 | 0.85 | TRIM24 (0.34) | — | |
| SCHEMBL31241037 | 0.81 | — | — | |
| SCHEMBL2310348 | 0.79 | — | — | |
| SCHEMBL10487376 | 0.76 | — | — | |
| SCHEMBL3160423 | 0.75 | — | — | |
| SCHEMBL9281136 | 0.72 | — | — | |
| SCHEMBL28266530 | 0.71 | CA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011632-A1 | HYDROXIMIC ACID COMPOUNDS CONTAINING TETRAHYDROBENZO[4,5]FURANO[2,3-C]PYRIDINE, PREPARATION METHOD THEREFOR, AND USES THEREOF | 浙江大学 | 2025-01-16 | — | — | WO | claimed |
| CN-117603219-A | P-glycoprotein inhibitor and preparation method and application thereof | 浙江大学 | 2024-02-27 | — | — | CN | claimed |
| CN-117088891-A | Tetrahydrobenzo [4,5] furan [2,3-C ] pyridine hydroxamic acid compound and preparation method and application thereof | 浙江大学 | 2023-11-21 | — | — | CN | claimed |
| CN-114276359-B | Preparation method of 1,2,3, 4-tetrahydrobenzo [4,5] furan [2,3-C ] pyridine derivative | 浙江大学 | 2023-05-05 | — | — | CN | claimed |
| CN-110872264-B | Cis-tetrahydrobenzofuran compound containing Z, E-diene outside ring and synthesis method thereof | 河南师范大学 | 2023-01-24 | — | — | CN | claimed |
| CN-110804035-B | Tetrahydrobenzofuran Mannich alkali compounds, and preparation method and application thereof | 三峡大学 | 2022-11-18 | — | — | CN | claimed |
| US-20220213114-A1 | PYRANOPYRAZOLE AND PYRAZOLOPYRIDINE IMMUNOMODULATORS FOR TREATMENT OF AUTOIMMUNE DISEASES | THE ROCKEFELLER UNIVERSITY (US) | 2022-07-07 | — | — | US | claimed |
| US-11312723-B2 | Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseases | THE ROCKEFELLER UNIVERSITY (US) | 2022-04-26 | — | — | US | claimed |
| CN-114276359-A | Preparation method of 1,2,3, 4-tetrahydrobenzo [4,5] furan [2,3-C ] pyridine derivative | 浙江大学 | 2022-04-05 | — | — | CN | claimed |
| CN-109475530-B | Aminoacyl indazole immunomodulators for treating autoimmune diseases | 洛克菲勒大学 | 2022-03-01 | — | — | CN | claimed |
| US-20060194836-A1 | Novel compounds having 4-pyridylalkylthio group as substituent | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2006-08-31 | — | — | US | claimed |
| EP-1602647-A1 | NOVEL COMPOUND HAVING 4-PYRIDYLALKYLTHIO GROUP AS SUBSTITUENT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-12-07 | — | — | EP | claimed |
| US-20050261303-A1 | N-phenyl-(2r,5s) dimethylpiperadine derivative | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | US | claimed |
| EP-1557411-A1 | N-PHENYL-(2R,5S)DIMETHYLPIPERADINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2005-07-27 | — | — | EP | claimed |
| EP-0831094-B1 | FUSED POLYCYCLIC HETEROCYCLE DERIVATIVES | EISAI CO LTD (JP) | 2004-12-08 | — | — | EP | claimed |
| EP-0690054-B1 | 1-Amino-2-cyclohexene derivatives and production process therefor | KURARAY CO (JP) | 2002-11-20 | — | — | EP | claimed |
| US-5952335-A | ANTITUMOR AGENTS | EISAI CO., LTD. (JP) | 1999-09-14 | — | — | US | claimed |
| EP-0831094-A1 | FUSED POLYCYCLIC HETEROCYCLE DERIVATIVES | Eisai Co., Ltd. (JP) | 1998-03-25 | — | — | EP | claimed |
| US-5587486-A | CONDENSATION; CARBONYLATION; HYDROLYSIS; INTERMEDIATES IN THE PRODUCTION OF MEDICINAL AND AGRICULTURAL AGENTS | KURARAY CO., LTD. (JP) | 1996-12-24 | — | — | US | claimed |
| EP-0690054-A1 | 1-Amino-2-cyclohexene derivatives and production process therefor | KURARAY CO., LTD. (JP) | 1996-01-03 | — | — | EP | claimed |