Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.62 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.62 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.60 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614749 | 0.91 | GPR17 (0.69) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614759 | 0.91 | GPR17 (0.63) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614756 | 0.91 | GPR17 (0.65) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614754 | 0.91 | GPR17 (0.67) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614753 | 0.90 | P2RY12 (0.68) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614787 | 0.89 | TAS1R3 (0.69) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614737 | 0.88 | P2RY12 (0.65) | GPR17P2RY1P2RY12P2RY2P2RY6 | |
| SCHEMBL13614755 | 0.88 | GPR17 (0.63) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614785 | 0.88 | TAS1R3 (0.70) | GPR17TAS1R3TAS1R1P2RY1P2RY12 | |
| SCHEMBL13614795 | 0.87 | TAS1R3 (0.66) | GPR17TAS1R3TAS1R1P2RY1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | disclosed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | disclosed |
| US-7435724-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICAL, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435724-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICAL, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. | 2007-10-18 | — | — | US | disclosed |
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | PNKP, ENTPD5, ENPP1 | GPR17 1564/4885TAS1R3 4619/4885TAS1R1 4739/4885 |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | PNKP, ENTPD5, ENPP1 | GPR17 1564/4885TAS1R3 4619/4885TAS1R1 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.