Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.60 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.60 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.57 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614759 | 0.94 | GPR17 (0.63) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614794 | 0.93 | TAS1R3 (0.65) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614793 | 0.91 | TAS1R3 (0.67) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614787 | 0.90 | TAS1R3 (0.69) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614756 | 0.89 | GPR17 (0.65) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614767 | 0.87 | P2RY12 (0.62) | TAS1R3TAS1R1ADORA1P2RY12P2RY2 | |
| SCHEMBL13614795 | 0.87 | TAS1R3 (0.66) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614785 | 0.87 | TAS1R3 (0.70) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614754 | 0.87 | GPR17 (0.67) | TAS1R3TAS1R1ADORA1P2RY12GPR17 | |
| SCHEMBL13614786 | 0.87 | P2RY12 (0.69) | TAS1R3TAS1R1ADORA1P2RY12GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | disclosed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | disclosed |
| US-7435724-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICAL, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435724-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICAL, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. | 2007-10-18 | — | — | US | disclosed |
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | PNKP, ENTPD5, ENPP1 | TAS1R3 4619/4885TAS1R1 4739/4885ADORA1 691/4885 |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | PNKP, ENTPD5, ENPP1 | TAS1R3 4619/4885TAS1R1 4739/4885ADORA1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.