SCHEMBL13614897

SCHEMBL13614897

Fc1ccccc1-c1cc(F)c(Cl)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.47
PTPN1 P18031 1/20 0.47
PDK2 Q15119 1/20 0.43
ACMSD Q8TDX5 1/20 0.42
ALOX5AP P20292 2/20 0.41
FEN1 P39748 2/20 0.41
TNKS O95271 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
BACE1 P56817 1/20 0.41
TRPA1 O75762 1/20 0.41
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
DHODH Q02127 2/20 0.40
ERN1 O75460 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAP4K4 O95819 1/20 0.39
NPC1 O15118 1/20 0.38
APEX1 P27695 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28116695 0.85 PTPRC (0.54) PTPRCPTPN1PDK2ACMSDALOX5AP
SCHEMBL30665737 0.83 PTPRC (0.48) PTPRCPTPN1PDK2ACMSDALOX5AP
SCHEMBL13439489 0.83 PTPRC (0.48) PTPRCPTPN1PDK2ACMSDALOX5AP
SCHEMBL18857327 0.81 FEN1 (0.45) PTPRCPTPN1PDK2ALOX5APFEN1
SCHEMBL31047274 0.80 ADORA2A (0.49) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL16151213 0.80 ADORA2A (0.49) PTPRCPTPN1ACMSDBACE1TRPA1
SCHEMBL31067169 0.80 PTPRC (0.52) PTPRCPTPN1PDK2ACMSDALOX5AP
SCHEMBL13615027 0.80 PTPRC (0.52) PTPRCPTPN1PDK2ACMSDALOX5AP
SCHEMBL1982001 0.80 PTPRC (0.43) PTPRCPTPN1PDK2ACMSDALOX5AP
SCHEMBL1337591 0.80 FEN1 (0.42) PTPRCPTPN1ACMSDALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed