Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555375 | 0.92 | PRKCZ (0.58) | PRKCZIMPDH2CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL8338721 | 0.92 | PRKCZ (0.58) | PRKCZIMPDH2CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL2616771 | 0.92 | CYP2A6 (0.59) | PRKCZCYP2A6IMPDH2CYP1A2CYP19A1 | |
| SCHEMBL30969150 | 0.92 | CYP2A6 (0.59) | PRKCZCYP2A6IMPDH2CYP1A2CYP19A1 | |
| SCHEMBL28302611 | 0.87 | PRKCZ (0.56) | PRKCZIMPDH2CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL8338092 | 0.85 | PRKCZ (0.68) | PRKCZIMPDH2CYP1A2CYP11B2CYP11B1 | |
| SCHEMBL23555378 | 0.85 | PRKCZ (0.68) | PRKCZIMPDH2CYP1A2CYP11B2CYP11B1 | |
| SCHEMBL24621868 | 0.84 | CYP2A6 (0.54) | PRKCZCYP2A6IMPDH2CYP1A2CYP19A1 | |
| SCHEMBL13670757 | 0.84 | CYP2A6 (0.54) | PRKCZCYP2A6IMPDH2CYP1A2CYP19A1 | |
| SCHEMBL9887365 | 0.84 | CYP2A6 (0.54) | CYP2A6CYP1A2CYP11B2CYP11B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611863-B2 | Selective staining of biomembranes using voltage-sensitive dyes | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2009-11-03 | — | — | US | disclosed |