SCHEMBL13615328

SCHEMBL13615328

Nc1cc2c(O)c(/N=N/c3ccc(/N=N/c4cnc5ccc(SOOO)cc5c4)c4ccc(C(=O)O)nc34)c(SOOO)cc2cc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.41
ENPP2 Q13822 2/20 0.32
PHLPP2 Q6ZVD8 1/20 0.31
CD40 P25942 1/20 0.31
CD40LG P29965 1/20 0.31
SENP3 Q9H4L4 2/20 0.30
SENP2 Q9HC62 2/20 0.30
SENP1 Q9P0U3 2/20 0.30
SUMO2 P61956 1/20 0.30
SUMO1 P63165 1/20 0.30
SENP7 Q9BQF6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13921645 0.96 PTPN11 (0.38) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13921648 0.96 PTPN11 (0.38) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13615324 0.89 PTPN11 (0.37) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13615333 0.87 PTPN11 (0.42) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13629444 0.83 ENPP2 (0.45) PTPN11ENPP2CD40CD40LGSENP3
SCHEMBL13934929 0.82 ENPP2 (0.43) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13935731 0.82 ENPP2 (0.43) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13615303 0.81 PTPN11 (0.53) PTPN11ENPP2PHLPP2CD40CD40LG
SCHEMBL13615108 0.80 PTPN11 (0.60) PTPN11ENPP2PHLPP2SENP3SENP2
SCHEMBL13615291 0.80 MEN1 (0.42) PTPN11ENPP2PHLPP2CD40CD40LG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275742-A1 COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2009-11-05 US disclosed