Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.50 |
| ▸ | PDE2A | O00408 | 5/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27879146 | 0.98 | EPHX2 (0.49) | EPHX2PDE2ASLC7A5CTSKNAAA | |
| Water SCHEMBL27879127 | 0.82 | EPHX2 (0.38) | EPHX2PDE2AGRM2 | |
| SCHEMBL13555174 | 0.79 | SCN5A (0.42) | EPHX2PDE2AGPR3GRM2 | |
| SCHEMBL12566385 | 0.78 | EPHX2 (0.53) | EPHX2PDE2ASLC7A5GPR3 | |
| SCHEMBL2093568 | 0.77 | EPHX2 (0.51) | EPHX2PDE2ASLC7A5CTSKNAAA | |
| SCHEMBL19033849 | 0.75 | EPHX2 (0.50) | EPHX2PDE2ASLC7A5CTSKNAAA | |
| SCHEMBL425877 | 0.75 | EPHX2 (0.50) | EPHX2PDE2ASLC7A5 | |
| SCHEMBL1253983 | 0.75 | EPHX2 (0.54) | EPHX2PDE2ASLC7A5CTSKNAAA | |
| SCHEMBL7779423 | 0.75 | EPHX2 (0.50) | EPHX2PDE2ASLC7A5CTSKNAAA | |
| SCHEMBL2093572 | 0.75 | EPHX2 (0.50) | EPHX2PDE2ASLC7A5CTSKNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198913-B2 | Nitroimidazooxazines and their uses in anti-tubercular therapy | GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) | 2015-12-01 | — | — | US | disclosed |
| EP-2459571-B1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | GLOBAL ALLIANCE FOR TB DRUG DEV (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-1756064-B1 | PYRAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2008-05-14 | — | — | EP | disclosed |