Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303792 | 0.90 | JAK2 (0.38) | JAK2TRIM58DHFRMAP4K4PRMT5 | |
| SCHEMBL24742412 | 0.88 | JAK2 (0.33) | JAK2DHFRMAP4K4PRMT5MKNK1 | |
| SCHEMBL13615943 | 0.86 | CYP1A2 (0.33) | ALDH1A1CYP1A2THRBHPGDHSD17B10 | |
| SCHEMBL13615760 | 0.86 | CYP1A2 (0.33) | ALDH1A1CYP1A2THRBHPGDHSD17B10 | |
| SCHEMBL16303789 | 0.85 | JAK2 (0.39) | JAK2TRIM58DHFRMAP4K4PRMT5 | |
| SCHEMBL13615820 | 0.81 | TRIM58 (0.35) | JAK2TRIM58DHFRMAP4K4PLA2G2A | |
| SCHEMBL17083517 | 0.81 | JAK2 (0.37) | JAK2TRIM58DHFRMAP4K4ESR2 | |
| SCHEMBL24169618 | 0.80 | MEN1 (0.41) | JAK2TRIM58DHFRALDH1A1HPGD | |
| SCHEMBL26573474 | 0.80 | MEN1 (0.41) | JAK2TRIM58DHFRALDH1A1HPGD | |
| SCHEMBL26573606 | 0.78 | MEN1 (0.40) | JAK2TRIM58DHFRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090273278-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090273278-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | OCIAD1, OCIAD2, ORMDL3 | JAK2 4018/4885TRIM58 4434/4885DHFR 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.