Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 8/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.37 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615887 | 0.85 | P2RY6 (0.43) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL13615610 | 0.85 | ABL1 (0.38) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL15691436 | 0.80 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL19841274 | 0.79 | P2RY6 (0.60) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL6930835 | 0.79 | P2RY6 (0.60) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL6930829 | 0.79 | P2RY6 (0.60) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL16904896 | 0.78 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL14429055 | 0.78 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL14440571 | 0.78 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL10072488 | 0.77 | POLB (0.43) | P2RY6P2RY14NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |